Research Interests
As a bioanalytical chemist, I am interested in using my knowledge of chemistry to design and execute novel methods of measuring living systems. I am particularly interested in the fundamental unit of living systems: individual cells. To measure chemical reactions in individual cells, I am (1) developing molecular tools to measure how cells respond to stress and (2) adapting a specific method of single-cell analysis, termed microfluidic chemical cytometry, for new applications. All of this work is undertaken in collaboration with my undergraduate research students.
Current Projects
- Application of fluorescently labeled peptide substrate reporters to enzyme assays in diverse species
- Capillary electrophoresis-based assays of enzyme activity
- Methods for measurement of reactive oxygen species
- Microfluidic devices for single-cell analysis
- Single-cell analysis of stress response in Dictyostelium discoideum and in Tetrahymena thermophila
For recent updates, visit the Lab Updates page.
Previous Research
- Postdoctoral Research, Allbritton Laboratory, University of North Carolina, 2010-2013
- Graduate Research, Jacobson Laboratory, Indiana University, 2004-2009
- Undergraduate Research, Spence and Martin Laboratories, Saint Louis University, 2001-2004